Item Type | Name |
Academic Article
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Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.
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Concept
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Drug Resistance, Neoplasm
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Academic Article
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Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation.
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Academic Article
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Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells.
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Academic Article
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Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.
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Academic Article
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The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
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Academic Article
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Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells.
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Academic Article
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Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer.
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Academic Article
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Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.
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Academic Article
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Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms.
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Academic Article
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Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol.
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Academic Article
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Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
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Academic Article
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Novel approaches for chemosensitization of breast cancer cells: the E1A story.
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Academic Article
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Induction of Akt activity by chemotherapy confers acquired resistance.
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Academic Article
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Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.
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Academic Article
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FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization.
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Academic Article
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Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis.
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Academic Article
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Chemo-signal therapy, an emerging new approach to modify drug resistance in breast cancer.
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Academic Article
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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.
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Academic Article
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Dysregulation of microRNAs in cancer.
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Academic Article
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Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides.
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Academic Article
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P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.
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Academic Article
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ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells.
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Academic Article
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Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.
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Academic Article
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Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors.
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Academic Article
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Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells.
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Academic Article
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MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer.
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Academic Article
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The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer.
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Academic Article
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The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells.
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Academic Article
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The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to?hyperactivate AKT?and confer resistance to AKT?inhibitors.
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Academic Article
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Lymphotoxin-? Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer.
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Academic Article
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ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.
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Academic Article
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The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer.
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Academic Article
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The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells.
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Academic Article
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EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer.
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Academic Article
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Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with ?-blockers.
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Academic Article
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Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
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Academic Article
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EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma.
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Academic Article
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Targeting PKCd as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer.
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Academic Article
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Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression.
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Academic Article
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Cigarette smoke-induced LKB1/AMPK pathway deficiency reduces EGFR TKI sensitivity in NSCLC.
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Academic Article
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TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis.
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Academic Article
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Endothelial p130cas confers resistance to anti-angiogenesis therapy.
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Academic Article
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Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma.
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